COMPOSITION CONTAINING INDUCER OF SIRT1 EXPRESSION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK
    1.
    发明申请
    COMPOSITION CONTAINING INDUCER OF SIRT1 EXPRESSION FOR PREVENTING OR TREATING SEPSIS OR SEPTIC SHOCK 有权
    包含SIRT1表达诱发剂的组合物,用于预防或治疗食欲或分解性震动

    公开(公告)号:US20130150555A1

    公开(公告)日:2013-06-13

    申请号:US13818847

    申请日:2012-02-17

    IPC分类号: A61K38/21

    CPC分类号: A61K38/215 A61P31/04

    摘要: The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Therefore, the inducer of SIRT1 expression is useful for preventing or treating sepsis or septic shock.

    摘要翻译: 本发明涉及含有用于预防或治疗败血症或败血性休克的SIRT1诱导剂(沉默交配型信息调节2同系物)表达的组合物。 SIRT1表达的诱导物可以通过减少促炎细胞因子和增加抗炎细胞因子,显着降低败血症或败血性休克引起的死亡率。 因此,SIRT1表达诱导剂可用于预防或治疗败血症或败血性休克。