发明申请
US20130157331A1 PNP GENE MODIFICATION FOR IMPROVED XYLOSE UTILIZATION IN ZYMOMONAS
有权
用于改善ZYMOMONAS中的XYLOSE利用的PNP基因修饰
- 专利标题： PNP GENE MODIFICATION FOR IMPROVED XYLOSE UTILIZATION IN ZYMOMONAS
- 专利标题（中）： 用于改善ZYMOMONAS中的XYLOSE利用的PNP基因修饰
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申请号： US13711646申请日： 2012-12-12
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公开(公告)号： US20130157331A1公开(公告)日： 2013-06-20
- 发明人: PERRY G. CAIMI , Min Qi , Luan Tao , Paul V. Viitanen , Jianjun Yang
- 申请人： E I Du Pont De Nemours And Company
- 申请人地址： US DE Wilmington
- 专利权人： E I Du Pont De Nemours And Company
- 当前专利权人： E I Du Pont De Nemours And Company
- 当前专利权人地址： US DE Wilmington
- 主分类号： C12N15/74
- IPC分类号： C12N15/74
摘要：
The endogenous pnp gene encoding polynucleotide phosphorylase in the Zymomonas genome was identified as a target for modification to provide improved xylose utilizing cells for ethanol production. The cells are in addition genetically modified to have increased expression of ribose-5-phosphate isomerase (RPI) activity, as compared to cells without this genetic modification, and are not limited in xylose isomerase activity in the absence of the pnp modification.
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