发明申请
US20130172532A1 METHOD FOR MAKING RHENIUM-186/188 LABELED HUMAN SERUM ALBUMIN MICROSPHERES AND KIT FOR MAKING THE SAME AND METHOD FOR USING THE KIT
有权
制备RHENIUM-186/188标记人血清白蛋白微球的方法及其制备方法及其使用方法
- 专利标题： METHOD FOR MAKING RHENIUM-186/188 LABELED HUMAN SERUM ALBUMIN MICROSPHERES AND KIT FOR MAKING THE SAME AND METHOD FOR USING THE KIT
- 专利标题（中）： 制备RHENIUM-186/188标记人血清白蛋白微球的方法及其制备方法及其使用方法
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申请号： US13538105申请日： 2012-06-29
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公开(公告)号： US20130172532A1公开(公告)日： 2013-07-04
- 发明人: CHIA-YU YU , TE-WEI LEE , SU-JUNG CHEN , LIANG-CHENG CHEN , CHIEN-HONG LIN
- 申请人： CHIA-YU YU , TE-WEI LEE , SU-JUNG CHEN , LIANG-CHENG CHEN , CHIEN-HONG LIN
- 申请人地址： TW Taoyuan County
- 专利权人： Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
- 当前专利权人： Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan
- 当前专利权人地址： TW Taoyuan County
- 优先权： TW100149875 20111230
- 主分类号： C07K14/765
- IPC分类号： C07K14/765
摘要：
The present invention relates to a method for preparing 186/188Re-labeled human serum albumin (HSA) microspheres by 186/188Re(I)-tricarbonyl ion. This radioactive particle can be subjected to radioembolization for liver tumor. In this method, 186/188Re(I)-tricarbonyl ion (186/188Re(OH2)3(CO)3)+) are employed as a precursor for directly labeling HSA microspheres with 186/188Re at appropriate temperature.