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公开(公告)号:US20240228663A9
公开(公告)日:2024-07-11
申请号:US18302869
申请日:2023-04-19
发明人: Ming-Cheng Chang , Ping-Fang Chiang , Yu-Jen Kuo
CPC分类号: C07K16/40 , A61K51/0497 , A61P35/00 , A61K2039/505 , C07K2317/565 , C07K2317/76
摘要: Disclosed herein an isolated neutralizing antibody, which is capable of specifically binding to chitinase-3-like protein-1 (YKL-40) and uses thereof. The neutralizing antibody can further conjugate with a metal chelator to form an antibody complex. Further, labeling the antibody complex with a radioactive metal nuclide results in formation of a radioactive antibody complex, which can be used as a contrast agent and treatment for YKL-40 over-expression-related diseases. The radioactive antibody complex can specifically bind to YKL-40, and can be used for diagnosis and the preparation of the use of the treatment for cancers related to YKL-40 over-expression.
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2.
公开(公告)号:US20240062924A1
公开(公告)日:2024-02-22
申请号:US17968862
申请日:2022-10-19
发明人: CHING-WEI YANG , KUEI-JEN CHENG , YING-WEI LIN , CHIEN-FU CHEN
IPC分类号: G21C17/06
CPC分类号: G21C17/06
摘要: A device, which is used to inspect the confinement boundary of a vertical spent nuclear fuel storage canister during operation, includes a vertical spent nuclear fuel storage unit, a lifting unit, a transferring unit and an inspection platform. The vertical spent nuclear fuel storage unit includes a vertical storage canister and a storage overpack. The vertical storage canister is configured for storing spent nuclear fuels, and the storage overpack is configured for storing the vertical storage canister. The lifting unit, connected with the vertical storage canister, is configured for lifting the vertical storage canister. The transferring unit, connected with the lifting unit, is configured for protecting the lifted vertical storage canister. The inspection platform, connected with the transferring unit and the storage overpack, is configured for creating more space with sufficient shielding for the usage of inspecting the confinement boundary of the vertical storage canister.
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公开(公告)号:US11897172B2
公开(公告)日:2024-02-13
申请号:US17464776
申请日:2021-09-02
发明人: Hung-Hsien Ku , Ning-Yih Hsu , Han-Jou Lin , Tai-Feng Hung , Qiao-Ya Chen
IPC分类号: B29C43/00 , B29C43/24 , B29B9/02 , B29C43/52 , B29C43/46 , C08K3/04 , D03D15/275 , D03D15/25 , H01M8/18 , C08K7/06 , B29K101/10 , B29K101/12
CPC分类号: B29C43/006 , B29B9/02 , B29C43/003 , B29C43/24 , B29C43/46 , B29C43/52 , C08K3/04 , C08K7/06 , D03D15/25 , D03D15/275 , H01M8/188 , B29K2101/10 , B29K2101/12 , C08K2201/001
摘要: A polar plate is fabricated. The polar plate is flexible and made of a plastic graphite composite. No matter a supporting member is used for calendering or not, a thin polar plate with controllable thickness is fabricated. The polar plate is excellent in blocking the through-transmission of vanadium ions and the limit of blending ratio of conductive carbon is broken through. The longitudinal through-transmission volume resistivity (proportional resistance to thickness) is greatly improved by adjusting the blending ratio of conductive carbon for meeting the demand of conductivity. In the mean time, the present invention strengthens the rigidity required for the thin polar plate while providing large-area polar plate fabrication for industrial use and convenience and provides a cooling and pressing method for patterning a composite polar plate. An integrated mold is thus obtained to replace the conventional polar plate which needs to be processed and prepared with runner.
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公开(公告)号:US20240024518A1
公开(公告)日:2024-01-25
申请号:US18099188
申请日:2023-01-19
发明人: Shiu-Wen LIU , Yi-Jhih CHEN , Wei-Hsi CHEN , Yu CHANG , Cheng-Fang HSU
IPC分类号: A61K51/04
CPC分类号: A61K51/04
摘要: The present invention provides a contrast agent which is efficiently and specifically absorbed by tumor cells, suitable for use in single photon emission computed tomography for the diagnosis, efficacy assessment and tumor tracking of neuroblastoma, pheochromocytoma or congestive heart failure.
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公开(公告)号:US11658341B2
公开(公告)日:2023-05-23
申请号:US16921062
申请日:2020-07-06
发明人: Tien-Hsiang Hsueh , Shang-En Liu , Min-Chuan Wang , Bo-Hsien Wu , Shu-Mei Chang
IPC分类号: H01M10/0565 , H01M10/0567 , H01M10/0525 , H01M10/058 , H01M10/42
CPC分类号: H01M10/0565 , H01M10/058 , H01M10/0525 , H01M10/0567 , H01M10/4235 , H01M2300/0082 , H01M2300/0085
摘要: A method for manufacturing a gel-state flame-retardant electrolyte film includes the steps of: preparing a first solution having a high boiling-point solvent; adding a solid-state polymer material into the first solution, and performing a heating and stirring process to form a second solution; adding a flame-retardant electrolyte material and a flame-retardant water-absorbent material into the second solution for forming a third solution by well mixing; forming the third solution into a viscous matter; and, solidifying the viscous matter to form the gel-state flame-retardant electrolyte film. In addition, a gel-state flame-retardant electrolyte film, a gel-state electrolyte battery and a method for manufacturing the gel-state electrolyte battery are also provided.
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公开(公告)号:US20230136060A1
公开(公告)日:2023-05-04
申请号:US17962614
申请日:2022-10-10
发明人: MEI-HUI WANG , KUN-LIANG LIN , CHUAN-YI CHIEN , HUNG-MAN YU
摘要: The method is capable of effectively labeling the nanodiamonds with radioactive gallium and can be operated at room temperature, and therefore is convenient to operate and does not require further purification to obtain the nanodiamonds labelled with radioactive gallium with a purity of at least 99%
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7.
公开(公告)号:US11370701B2
公开(公告)日:2022-06-28
申请号:US17366010
申请日:2021-07-01
发明人: Yung-Ching Liu , En-Shih Chen , Cheng-Chang Hsieh
摘要: A solar control film with improved moisture resistance function is provided. The solar control film includes a flexible substrate, at least one infrared-reflective composite layer and an outer dielectric layer. The infrared-reflective composite layer includes a dielectric sublayer and a metal sublayer. The dielectric sublayer is disposed on the flexible substrate, and the material of the dielectric sublayer includes TiO2. The metal sublayer is disposed on the dielectric sublayer, and includes 8.3-16.4 atomic % Ag, 0.5-1.0 atomic % Ti, 81.0-90.9 atomic % N, and 0.3-0.6 atomic % noble metal, and the noble metal is Au, Pd or any combinations thereof. The outer dielectric layer is disposed on the infrared-reflective composite layer, and the material of the outer dielectric layer includes TiO2. In this way, the provided solar control film can effectively suppress of forming white spots without significantly sacrificing its original function and characteristics.
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公开(公告)号:US11369268B2
公开(公告)日:2022-06-28
申请号:US16885478
申请日:2020-05-28
发明人: Fan-Pin Tseng , Yu-Ching Ni , Wen-Bin Lin
摘要: A brain-function image data augmentation method includes: a step of providing a target database including a plurality of image-data information; a step of, based on a plurality of image-data expected information in an expectation-value database, calculating a ratio of the plurality of image-data expected information with respect to different ages; a step of, based on the plurality of image-data information and the ratio, obtaining image-data ratio information with respect to an estimated age; a step of establishing a relationship for each pair of the image-data information and the image-data expected information; a step of, based on the relationship, the ratio and the image-data information, calculating an estimated image-data information with respect to the estimated age; and, a step of combining linearly the estimated image-data information and the image-data ratio information so as to generate an augmented image-data information with respect to the estimated age.
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公开(公告)号:US20220125761A1
公开(公告)日:2022-04-28
申请号:US17126364
申请日:2020-12-18
IPC分类号: A61K31/395 , C01G15/00
摘要: Disclosed herein is a complex, a contrast agent and the method for treating a disease related to CXCR4 receptor. The complex is configured to bind the CXCR4 receptor, and is used as a medicament for diagnosis and treatment of cancers and other indications related to the CXCR4 receptor.
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公开(公告)号:US20210088865A1
公开(公告)日:2021-03-25
申请号:US16728137
申请日:2019-12-27
发明人: TIEN-FU KO , CHEN-TE CHANG , PO-WEN CHEN , HSIN-FU YU , KUO-CHUAN HO , SHENG-CHUAN HSU , JIN-YU WU , WEN-FA TSAI , HWEN-FEN HONG
IPC分类号: G02F1/155 , G02F1/1524 , E06B9/24
摘要: A method for fabricating an electrochromic device includes: depositing a first transparent film on a first substrate; depositing a first mesh structure on the first transparent film; depositing a second transparent film on the first mesh structure; depositing an electrochromic layer of WO3 or MoO3 on the second transparent film by an arc-plasma process to form a first electrode structure; depositing a third transparent film on a second substrate; depositing a second mesh structure on the third transparent film; depositing a fourth transparent film on the second mesh structure; forming an ion storage layer of PB on the fourth transparent film to produce a second electrode structure; binding the first and second electrode structures by having the electrochromic layer to face the ion storage layer; and, forming an electrolyte layer between the first and second electrode structures to produce the electrochromic device. In addition, an electrochromic device is also provided.
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