发明申请
US20130179998A1 TRANSGENIC MOUSE MODEL EXPRESSING AMYLOID BETA 4-42 PEPTIDE 有权
转基因鼠模型表达4-42肽的淀粉样蛋白

  • 专利标题: TRANSGENIC MOUSE MODEL EXPRESSING AMYLOID BETA 4-42 PEPTIDE
  • 专利标题(中): 转基因鼠模型表达4-42肽的淀粉样蛋白
  • 申请号: US13702390
    申请日: 2010-06-08
  • 公开(公告)号: US20130179998A1
    公开(公告)日: 2013-07-11
  • 发明人: Thomas BayerOliver Wirths
  • 申请人: Thomas BayerOliver Wirths
  • 国际申请: PCT/EP2010/058024 WO 20100608
  • 主分类号: A01K67/027
  • IPC分类号: A01K67/027
TRANSGENIC MOUSE MODEL EXPRESSING AMYLOID BETA 4-42 PEPTIDE
摘要:
The present invention describes a novel transgenic mouse model for the common sporadic form of Alzheimer's disease. More particularly, the invention relates to a nucleotide sequence encoding Aβ 4-42 in functional linkage with at least a promoter, signal peptide sequence and a polyadenylation signal sequence, a cell and a transgenic non-human animal comprising said nucleotide sequence, and their respective use in screening methods.
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