发明申请
- 专利标题: TRANSGENIC MOUSE MODEL EXPRESSING AMYLOID BETA 4-42 PEPTIDE
- 专利标题(中): 转基因鼠模型表达4-42肽的淀粉样蛋白
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申请号: US13702390申请日: 2010-06-08
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公开(公告)号: US20130179998A1公开(公告)日: 2013-07-11
- 发明人: Thomas Bayer , Oliver Wirths
- 申请人: Thomas Bayer , Oliver Wirths
- 国际申请: PCT/EP2010/058024 WO 20100608
- 主分类号: A01K67/027
- IPC分类号: A01K67/027
摘要:
The present invention describes a novel transgenic mouse model for the common sporadic form of Alzheimer's disease. More particularly, the invention relates to a nucleotide sequence encoding Aβ 4-42 in functional linkage with at least a promoter, signal peptide sequence and a polyadenylation signal sequence, a cell and a transgenic non-human animal comprising said nucleotide sequence, and their respective use in screening methods.
公开/授权文献
- US09204623B2 Transgenic mouse model expressing amyloid β 4-42 peptide 公开/授权日:2015-12-08
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