发明申请
- 专利标题： P2X4 RECEPTOR ANTAGONIST
- 专利标题（中）： P2X4受体拮抗剂
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申请号： US13811909申请日： 2011-07-27
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公开(公告)号： US20130184459A1公开(公告)日： 2013-07-18
- 发明人: Masatoshi Ushioda , Shogo Sakuma , Toshiyasu Imai , Kazuhide Inoue
- 申请人： Masatoshi Ushioda , Shogo Sakuma , Toshiyasu Imai , Kazuhide Inoue
- 申请人地址： JP Chiyoda-ku, Tokyo
- 专利权人： NIPPON CHEMIPHAR CO., LTD.
- 当前专利权人： NIPPON CHEMIPHAR CO., LTD.
- 当前专利权人地址： JP Chiyoda-ku, Tokyo
- 优先权： JP2010-174240 20100803
- 国际申请： PCT/JP2011/067028 WO 20110727
- 主分类号： C07D239/70
- IPC分类号： C07D239/70 ; C07D403/10
摘要：
A compound having the following formula (II) or a pharmacologically acceptable salt thereof is used as a P2X4 receptor antagonist: wherein each of R11 and R12 is hydrogen, C1-8 alkyl or the like; R13 is hydrogen, C1-8 alkyl or the like; R14 is C1-8 alkoxy, hydroxyl, cyano, a heterocyclic group optionally having a substituent or the like; and the condensed ring consisting of W1 and the neighboring benzene ring is naphthalene ring or the like.
公开/授权文献
- US08680110B2 P2X4 receptor antagonist 公开/授权日：2014-03-25
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