发明申请
- 专利标题： POLYIMIDAZOLES FOR USE AS BILE ACID SEQUESTRANTS
- 专利标题（中）： 用作单酯酸序列的聚霉素
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申请号： US13581102申请日： 2011-02-24
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公开(公告)号： US20130189215A1公开(公告)日： 2013-07-25
- 发明人: Inez Lees , Kalpesh Biyani , Eric Connor , Scott Hecker , Hongmin Zhang , Michael James Cope , Elizabeth Goka , Angela Lee , Deidre Madsen , Jun Shao , Xinnan Zhang
- 申请人： Inez Lees , Kalpesh Biyani , Eric Connor , Scott Hecker , Hongmin Zhang , Michael James Cope , Elizabeth Goka , Angela Lee , Deidre Madsen , Jun Shao , Xinnan Zhang
- 申请人地址： US CA Santa Clara
- 专利权人： RELYPSA, INC.
- 当前专利权人： RELYPSA, INC.
- 当前专利权人地址： US CA Santa Clara
- 国际申请： PCT/US11/26102 WO 20110224
- 主分类号： C08F226/06
- IPC分类号： C08F226/06 ; A61K45/06 ; C08G73/06 ; A61K31/787
摘要：
The present invention provides crosslinked amine polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritus, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like.