- 专利标题： PYRIDAZINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS FOR TREATING MICRORNA VIRAL INFECTION
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申请号： US13813806申请日： 2011-08-02
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公开(公告)号： US20130190319A1公开(公告)日： 2013-07-25
- 发明人: Song Li , Hongliang Wang , Junhai Xiao , Xian Zhang , Lili Wang , Zhibing Zheng , Wu Zhong , Yunde Xie , Xingzhou Li , Xinbo Zhou , Guoming Zhao , Xiaokui Wang
- 申请人： Song Li , Hongliang Wang , Junhai Xiao , Xian Zhang , Lili Wang , Zhibing Zheng , Wu Zhong , Yunde Xie , Xingzhou Li , Xinbo Zhou , Guoming Zhao , Xiaokui Wang
- 申请人地址： CN BEIJING
- 专利权人： INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES
- 当前专利权人： INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES
- 当前专利权人地址： CN BEIJING
- 优先权： CN201010242472.X 20100802
- 国际申请： PCT/CN11/77896 WO 20110802
- 主分类号： C07D237/20
- IPC分类号： C07D237/20
摘要：
Disclosed are pyridazine derivatives represented by Formula I or pharmaceutically acceptable salts or hydrates thereof, pharmaceutical compositions comprising the compounds, methods of treating and/or preventing diseases or disorders associated with viral infections in patients using the compounds, and the use of the compounds in preparing the medicaments for treating and/or preventing diseases or disorders associated with viral infections. The compounds represented by Formula I have antiviral activity, especially anti-microRNA viral activity. Symbols in the compounds represented are described in the specification.