发明申请
- 专利标题： MODIFIED CLOSTRIDIAL TOXINS WITH ENHANCED TRANSLOCATION CAPABILITY AND ENHANCED TARGETING ACTIVITY
- 专利标题（中）： 具有增强转录能力和增强目标活动的改性离子毒素
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申请号： US11776043申请日： 2007-07-11
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公开(公告)号： US20130203148A1公开(公告)日： 2013-08-08
- 发明人: Lance E. Steward , Joseph Francis , Ester G. Fernandez-Salas , Marcella A. Gilmore , Shengwen Li , Kei Roger Aoki
- 申请人： Lance E. Steward , Joseph Francis , Ester G. Fernandez-Salas , Marcella A. Gilmore , Shengwen Li , Kei Roger Aoki
- 主分类号： C12N9/96
- IPC分类号： C12N9/96
摘要：
The specification discloses modified Clostridial toxins comprising a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain, a translocation facilitating domain and an enhanced targeting domain; polynucleotide molecules encoding such modified Clostridial toxins; and method of producing such modified Clostridial toxins.
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