发明申请
- 专利标题: Preparation for Improving Solubility of Poorly Soluble Drug
- 专利标题(中): 改善难溶性药物溶解度的准备
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申请号: US13825552申请日: 2011-09-29
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公开(公告)号: US20130203723A1公开(公告)日: 2013-08-08
- 发明人: Satoshi Sakuma , Hiroshi Ueda , Akira Mashimo , Hiroshi Murazato
- 申请人: Satoshi Sakuma , Hiroshi Ueda , Akira Mashimo , Hiroshi Murazato
- 国际申请: PCT/JP2011/072355 WO 20110929
- 主分类号: A61K9/00
- IPC分类号: A61K9/00
摘要:
The present invention relates to solubility improving preparation for enhancing the oral absorption of a poorly soluble drug, which is comprising (A) and (B); (A) a granulated substance which comprises (i) a poorly soluble drug having an acidic group in the molecule, (ii) an alkaline agent, (iii) a surfactant, and this granulated substance dose not substantially contain a disintegrator, (B) a disintegrator existing only in the external of the granulated substance.
公开/授权文献
- US09427402B2 Preparation for improving solubility of poorly soluble drug 公开/授权日:2016-08-30
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