- 专利标题: Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH
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申请号: US13697986申请日: 2011-05-13
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公开(公告)号: US20130210156A1公开(公告)日: 2013-08-15
- 发明人: Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
- 申请人: Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
- 国际申请: PCT/US11/36411 WO 20110513
- 主分类号: G01N21/75
- IPC分类号: G01N21/75
摘要:
Described herein are optical agents, including compositions, preparations and formulations, for monitoring the pH of a fluid. Optical agents described herein include photonic nanostructures and nanoassemblies including supramolecular structures, such as shell cross-linked micelles, that incorporate at least one linking group comprising one or more photoactive moieties that provide functionality as exogenous agents for a range of pH monitoring applications. Optical agents described herein comprise supramolecular structures having linking groups imparting useful optical and structural functionality. In an embodiment, for example, the presence of linking groups function to covalently cross link polymer components to provide a cross-linked shell stabilized supramolecular structure, and also impart useful optical functionality, for example by functioning as a fluorophore.