公开(公告)号：US10912936B2

公开(公告)日：2021-02-09

申请号：US16148701

申请日：2018-10-01

申请人： National Formosa University ,  National Taiwan University Hospital Yun-Lin Branch

发明人： Sung-An Lin ,  I-En Lin ,  Feng-Jung Yang ,  Hao-Ting Chiang

IPC分类号： A61M39/18 ,  A61M1/28 ,  A61M39/10 ,  A61M39/20

摘要： A tube-docking holding device includes a first connector bracket and a second connector bracket. The first connector bracket includes two shells. When the two shells are closed, a first accommodation space is surrounded for fixing a portion of a first connector assembly of a catheter. The second connector bracket includes a base body and a cover body. The base body includes a first inner shell and a first outer shell. The cover body includes a second inner shell and a second outer shell. When the cover body and the base body are closed, the first inner shell and the second inner shell surround and define a second accommodation space for fixing a portion of a second connector assembly of a dialysate tube. An interconnected guiding space is formed between the first inner shell and the first outer shell and between the second inner shell and the second outer shell.

公开(公告)号：USD891923S1

公开(公告)日：2020-08-04

申请号：US29625709

申请日：2017-11-12

申请人： Yun Lin

设计人： Yun Lin

公开(公告)号：USD852037S1

公开(公告)日：2019-06-25

申请号：US29623388

申请日：2017-10-25

申请人： Yun Lin

设计人： Yun Lin

公开(公告)号：US10273973B2

公开(公告)日：2019-04-30

申请号：US13578163

申请日：2011-02-03

申请人： Xinqian Zheng ,  Yun Lin ,  Yangjun Zhang ,  Mingyang Yang ,  Takahiro Bamba ,  Hideaki Tamaki

发明人： Xinqian Zheng ,  Yun Lin ,  Yangjun Zhang ,  Mingyang Yang ,  Takahiro Bamba ,  Hideaki Tamaki

IPC分类号： F04D17/10 ,  F04D29/42 ,  F04D29/68

摘要： A centrifugal compressor includes an asymmetric self-recirculating casing treatment that includes, on an inner face of a casing 10, a suction ring groove 1, a ring guide channel 2 and a back-flow ring groove 3 to form a self-recirculating channel. An axial distance Sr from an upstream end face of the suction ring groove 1 to an impeller full blade leading edge 4 or a width br of the suction ring groove 1 is represented as A·sin(α+θ0)+A0 and is distributed in a sinusoidal shape in a circumferential direction, an initial phase angle θ0 is in a range of 0°≤θ0≤360°, and a circumferential angle α of the casing 10 has a definition range of θ0≤α≤θ0+360°. In the expression, A denotes amplitude of distribution of the axial distance Sr or the width br, and A0 denotes an average of the axial distance Sr or the width br.

公开(公告)号：US09816522B2

公开(公告)日：2017-11-14

申请号：US13578188

申请日：2011-02-03

申请人： Xinqian Zheng ,  Yun Lin ,  Yangjun Zhang ,  Mingyang Yang ,  Takahiro Bamba ,  Hideaki Tamaki

发明人： Xinqian Zheng ,  Yun Lin ,  Yangjun Zhang ,  Mingyang Yang ,  Takahiro Bamba ,  Hideaki Tamaki

IPC分类号： F04D17/16 ,  F04D29/42 ,  F04D29/68

CPC分类号： F04D29/4213 ,  F04D29/685

摘要： A centrifugal compressor has a casing 7. In the casing 7 is formed a back-flow channel 9 to return fluid from a downstream position of an impeller full blade leading edge 6a to an upstream position of the impeller full blade leading edge 6a. The back-flow channel 9 includes a suction ring groove 9a and a back-flow ring groove 9b. The suction ring groove opens at the downstream position on the inner face 7a of the casing 7, and extends in the circumferential direction. The back-flow ring groove opens at the upstream position on the inner face 7a, and extends in the circumferential direction. Distribution in the circumferential direction of the axial-direction position of the suction ring groove 9a or a width of the suction ring groove 9a is asymmetric with reference to the rotation axis.

公开(公告)号：US09295650B2

公开(公告)日：2016-03-29

申请号：US13697149

申请日：2011-11-17

申请人： William L. Neumann ,  Richard B. Dorshow ,  John N. Freskos ,  Karen L. Wooley ,  Nam S. Lee ,  Yun Lin ,  Guorong Sun

发明人： William L. Neumann ,  Richard B. Dorshow ,  John N. Freskos ,  Karen L. Wooley ,  Nam S. Lee ,  Yun Lin ,  Guorong Sun

IPC分类号： A61K49/00 ,  A61K9/14 ,  A61K9/00 ,  A61K9/107 ,  A61K9/51 ,  A61K31/20 ,  A61K31/70 ,  A61K38/16 ,  A61K38/22 ,  A61K39/395 ,  A61M5/00

CPC分类号： A61K41/0057 ,  A61K9/0092 ,  A61K9/1075 ,  A61K9/146 ,  A61K9/5138 ,  A61K9/5192 ,  A61K31/20 ,  A61K31/337 ,  A61K31/351 ,  A61K31/70 ,  A61K31/704 ,  A61K38/08 ,  A61K38/16 ,  A61K38/22 ,  A61K45/06 ,  A61K47/6911 ,  A61K49/0021 ,  A61K49/0054 ,  A61K49/0082 ,  A61K49/0093 ,  A61M5/007 ,  A61K2300/00

摘要： The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for tandem optical imaging and therapy. Supramolecular structures and assemblies of the present invention include optically functional shell-cross linked micelles wherein optical functionality is achieved via incorporation of one or more linking groups that include one or more photoactive moieties. The present invention further includes imaging and therapeutic methods using one or more optical agents of the present invention including optically functional shell cross-linked micelles having an associated therapeutic agent.

摘要翻译： 本发明提供包含光学功能交联的超分子结构和用于串联光学成像和治疗的组合物的光学剂。 本发明的超分子结构和组件包括光学功能的壳交联胶束，其中通过引入一个或多个包含一个或多个光活性部分的连接基团来实现光学官能团。 本发明还包括使用本发明的一种或多种光学剂的成像和治疗方法，其包括具有相关治疗剂的光学功能性壳交联胶束。

公开(公告)号：US20160083605A1

公开(公告)日：2016-03-24

申请号：US14889047

申请日：2013-05-08

申请人： Shijun FENG ,  Yun LIN

发明人： Shijun FENG ,  Yun LIN

IPC分类号： C09D127/12 ,  D06M11/79 ,  D06M15/256

CPC分类号： C09D127/12 ,  C08K3/22 ,  C08K3/36 ,  C08K2003/2227 ,  C08K2003/2241 ,  C08K2003/2296 ,  C09D5/1668 ,  D06M11/79 ,  D06M15/248 ,  D06M15/256 ,  D06M23/08 ,  D06M2101/06 ,  D06M2101/20 ,  D06M2101/24 ,  D06M2101/34 ,  D06M2200/11 ,  D06M2200/12

摘要： Disclosed water and oil repellent coatings for textile fabrics having a low surface energy portion having a polyolefin having a Rf of 4 or less, and a nanometer portion which has nanoparticles. Also disclosed coated fabrics, as well as methods for making the coated fabrics.

摘要翻译： 公开了具有低表面能部分的织物的防水防油涂料，其具有Rf为4或更小的聚烯烃和具有纳米颗粒的纳米部分。 还公开了涂覆织物，以及制造涂覆织物的方法。

公开(公告)号：US09180107B2

公开(公告)日：2015-11-10

申请号：US12751375

申请日：2010-03-31

申请人： Hung-Yun Lin ,  Faith B. Davis ,  Paul J. Davis ,  Shaker A. Mousa

发明人： Hung-Yun Lin ,  Faith B. Davis ,  Paul J. Davis ,  Shaker A. Mousa

IPC分类号： A01N59/22 ,  A61K9/14 ,  A61K9/16 ,  A61K9/50 ,  A61K39/00 ,  A61K39/395 ,  C07K16/00 ,  C12P21/08 ,  A61K31/192 ,  A61K45/06 ,  A61K47/48

CPC分类号： A61K31/192 ,  A61K39/3955 ,  A61K45/06 ,  A61K47/6921 ,  A61K47/6935 ,  A61K47/6937 ,  A61K2300/00

摘要： Provided herein are compositions and methods for treating cancer by increasing the inhibitory effect of cetuximab on HIF1α expression by administering cetuximab in combination with anti-angiogenic thyroid hormone analogs such as tetrac or triac.

摘要翻译： 本文提供了通过施用西妥昔单抗联合抗血管生成甲状腺激素类似物如四或三联报来增加西妥昔单抗对HIF1α表达的抑制作用来治疗癌症的组合物和方法。

公开(公告)号：US09151297B2

公开(公告)日：2015-10-06

申请号：US13578101

申请日：2011-02-03

申请人： Xinqian Zheng ,  Yun Lin ,  Yangjun Zhang ,  Mingyang Yang ,  Takahiro Bamba ,  Hideaki Tamaki

发明人： Xinqian Zheng ,  Yun Lin ,  Yangjun Zhang ,  Mingyang Yang ,  Takahiro Bamba ,  Hideaki Tamaki

IPC分类号： F04D29/42 ,  F04D29/68

CPC分类号： F04D29/4213 ,  F04D29/685 ,  F05D2250/73

摘要： A centrifugal compressor includes an asymmetric self-recirculating casing treatment that includes, on an inner face of a casing 10, a suction ring groove 1, a ring guide channel 2 and a back-flow ring groove 3 to form a self-recirculating channel. A position or a width of the suction ring groove 1 is distributed in an arc shape in a circumferential direction, and the arc has a center angle α in a range of 0

摘要翻译： 离心压缩机包括不对称的自再循环壳体处理，其在壳体10的内表面上包括吸入环槽1，环形引导通道2和回流环槽3，以形成自再循环通道。 吸入环槽1的位置或宽度在圆周方向上分布成圆弧状，电弧的中心角α为0 <α<0.01; 30°的范围。

公开(公告)号：US08916367B2

公开(公告)日：2014-12-23

申请号：US13335647

申请日：2011-12-22

申请人： Thomas William Jeffries ,  JuYun Bae ,  Bernice Chin-yun Lin ,  Jennifer Rebecca Headman Van Vleet

发明人： Thomas William Jeffries ,  JuYun Bae ,  Bernice Chin-yun Lin ,  Jennifer Rebecca Headman Van Vleet

IPC分类号： C12P7/06 ,  C07K14/39 ,  C12P7/18

CPC分类号： C12N15/81 ,  C07K14/39 ,  C12P7/06 ,  C12P7/18 ,  Y02E50/17

摘要： Disclosed are nucleic acid constructs comprising coding sequences operably linked to a promoter not natively associated with the coding sequence. The coding sequences encode Pichia stipitis proteins that allow recombinant strains of Saccharomyces cerevisiae expressing the protein to grow on xylose, and allow or increase uptake of xylose by Pichia stipitis or Saccharomyces cerevisiae expressing the coding sequences. Expression of the coding sequences enhances uptake of xylose and/or glucose, allowing increased ethanol or xylitol production.

摘要翻译： 公开了包含编码序列的核酸构建体，所述编码序列可操作地连接到与编码序列本身无关联的启动子。 编码序列编码树干毕赤酵母蛋白，其允许表达蛋白质的酿酒酵母的重组菌株在木糖上生长，并允许或增加表达编码序列的毕赤酵母或酿酒酵母的木糖摄取。 编码序列的表达增强木糖和/或葡萄糖的吸收，允许增加乙醇或木糖醇的产生。