发明申请
- 专利标题: HETEROARYLOXYHETEROCYCLYL COMPOUNDS AS PDE10 INHIBITORS
- 专利标题(中): 作为PDE10抑制剂的异氟醚化合物
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申请号: US13892196申请日: 2013-05-10
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公开(公告)号: US20130253186A1公开(公告)日: 2013-09-26
- 发明人: Jennifer R. Allen , Daniel B. Horne , Essa Hu Harrington , Matthew R. Kaller , Holger Monenschein , Thomas T. Nguyen , Andreas Reichelt , Robert M. Rzasa
- 申请人: Amgen Inc.
- 申请人地址: US CA Thousand Oaks
- 专利权人: Amgen Inc.
- 当前专利权人: Amgen Inc.
- 当前专利权人地址: US CA Thousand Oaks
- 主分类号: C07D491/107
- IPC分类号: C07D491/107 ; C07D403/04 ; C07D487/04 ; C07D403/14 ; C07D401/14 ; C07D487/10 ; C07D401/04 ; C07D405/04 ; C07D401/06 ; C07D405/14 ; C07D409/14 ; C07D413/14 ; C07D471/04
摘要:
Heteroaryloxyheterocyclyl compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like.
公开/授权文献
- US09376450B2 Heteroaryloxyheterocyclyl compounds as PDE10 inhibitors 公开/授权日:2016-06-28
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