发明申请
- 专利标题： DIPHENYL SULFIDE DERIVATIVE AND PHARMACEUTICAL PRODUCT WHICH CONTAINS SAME AS ACTIVE INGREDIENT
- 专利标题（中）： 含硫酸盐衍生物和药物产品含有活性成分
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申请号： US13883847申请日： 2011-12-20
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公开(公告)号： US20130261089A1公开(公告)日： 2013-10-03
- 发明人: Kumi Ishikawa , Shigeru Koga , Yasushi Kohno , Kiyoshi Fujii , Ken Yoshikawa
- 申请人： Kumi Ishikawa , Shigeru Koga , Yasushi Kohno , Kiyoshi Fujii , Ken Yoshikawa
- 优先权： JP2010-284150 20101221
- 国际申请： PCT/JP2011/007111 WO 20111220
- 主分类号： C07F9/38
- IPC分类号： C07F9/38
摘要：
[Problem] To provide a diphenyl sulfide derivative which is useful as a pharmaceutical product that has excellent S1P3 antagonist activity.[Solution] The inventors have discovered that a diphenyl sulfide derivative represented by general formula (1) (wherein R1 represents an alkoxy group having 1-6 carbon atoms, R2 represents a propyl group or an allyl group, X represents methylene or an oxygen atom, and Z represents a halogen atom) has excellent S1P3 antagonist activity as a result of extensive researches for the production of a compound that has S1P3 antagonist activity.