A medical grade cleansing and numbing agent combination pad is disclosed. An example combination pad includes a pad impregnated with a cleansing agent and a numbing agent each in separate layers. Both the cleansing agent and the numbing agent are released through a same side of the pad without a user having to turn the pad over to apply both the cleansing agent and the numbing agent to a treatment area at substantially the same time. A barrier prevents the numbing agent from contacting the user during application to the treatment area.