发明申请
- 专利标题： METHODS, ASSAYS AND COMPOUNDS FOR TREATING BACTERIAL INFECTIONS BY INHIBITING METHYLTHIOINOSINE PHOSPHORYLASE
- 专利标题（中）： 通过抑制甲硫氨酸磷酸酶处理细菌感染的方法，测定和化合物
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申请号： US13884298申请日： 2011-11-28
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公开(公告)号： US20130274220A1公开(公告)日： 2013-10-17
- 发明人: Vern L. Schramm , Keith Clinch , Peter Charles Tyler , Gary Brian Evans , Richard Hubert Furneaux
- 申请人： Vern L. Schramm , Keith Clinch , Peter Charles Tyler , Gary Brian Evans , Richard Hubert Furneaux
- 申请人地址： NZ Lower Hutt US NY Bronx
- 专利权人： Industrial Research Limited,Albert Einstein College of Medicine of Yeshiva University
- 当前专利权人： Industrial Research Limited,Albert Einstein College of Medicine of Yeshiva University
- 当前专利权人地址： NZ Lower Hutt US NY Bronx
- 国际申请： PCT/US11/62208 WO 20111128
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K45/06 ; A61K31/519 ; C12Q1/48
摘要：
The present invention discloses methods for treating bacterial infections in a subject comprising administering to the subject a sub-growth inhibiting amount of a 5′-methylthioinosine phosphorylase (MTIP) inhibitor, as well as assays for identifying such inhibitors, and compounds and pharmaceutical compositions comprising the inhibitors.
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