发明申请
- 专利标题: 2,4-DIAMINO-PYRIMIDINES AS AURORA INHIBITORS
- 专利标题(中): 2,4-二氨基吡啶作为芳族抑制剂
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申请号: US13850711申请日: 2013-03-26
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公开(公告)号: US20130281429A1公开(公告)日: 2013-10-24
- 发明人: Stephan Karl ZAHN , Guido BOEHMELT , Andreas MANTOULIDIS , Ulrich REISER , Matthias TREU , Ulrich GUERTLER , Andreas SCHOOP , Flavio SOLCA , Ulrike TONTSCH-GRUNT , Ralph BRUECKNER , Charlotte REITHER , Lars HERFURTH , Oliver KRAEMER , Heinz STADTMUELLER , Harald ENGELHARDT
- 申请人: Stephan Karl ZAHN , Guido BOEHMELT , Andreas MANTOULIDIS , Ulrich REISER , Matthias TREU , Ulrich GUERTLER , Andreas SCHOOP , Flavio SOLCA , Ulrike TONTSCH-GRUNT , Ralph BRUECKNER , Charlotte REITHER , Lars HERFURTH , Oliver KRAEMER , Heinz STADTMUELLER , Harald ENGELHARDT
- 申请人地址: DE INGELHEIM AM RHEIN
- 专利权人: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
- 当前专利权人地址: DE INGELHEIM AM RHEIN
- 优先权: EP05106007.7 20050701
- 主分类号: C07D239/48
- IPC分类号: C07D239/48 ; C07D401/14 ; C07D401/12 ; C07D487/08 ; A61K31/5377 ; A61K45/06 ; A61K31/506 ; A61K31/505 ; A61K31/551 ; C07D403/12 ; C07D409/14
摘要:
The present invention encompasses compounds of general formula (1) wherein R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.
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