专利检索 ap:("Stephan Karl ZAHN" OR "Guido BOEHMELT" OR "Andreas MANTOULIDIS" OR "Ulrich REISER" OR "Matthias TREU" OR "Ulrich GUERTLER" OR "Andreas SCHOOP" OR "Flavio SOLCA" OR "Ulrike TONTSCH-GRUNT" OR "Ralph BRUECKNER" OR "Charlotte REITHER" OR "Lars HERFURTH" OR "Oliver KRAEMER" OR "Heinz STADTMUELLER" OR "Harald ENGELHARDT") AND inv:"Lars HERFURTH" 第 1 页

1.

发明申请
2,4-DIAMINO-PYRIMIDINES AS AURORA INHIBITORS 审中-公开
标题翻译： 2,4-二氨基吡啶作为芳族抑制剂

公开(公告)号：US20130281429A1

公开(公告)日：2013-10-24

申请号：US13850711

申请日：2013-03-26

申请人： Stephan Karl ZAHN , Guido BOEHMELT , Andreas MANTOULIDIS , Ulrich REISER , Matthias TREU , Ulrich GUERTLER , Andreas SCHOOP , Flavio SOLCA , Ulrike TONTSCH-GRUNT , Ralph BRUECKNER , Charlotte REITHER , Lars HERFURTH , Oliver KRAEMER , Heinz STADTMUELLER , Harald ENGELHARDT

发明人： Stephan Karl ZAHN , Guido BOEHMELT , Andreas MANTOULIDIS , Ulrich REISER , Matthias TREU , Ulrich GUERTLER , Andreas SCHOOP , Flavio SOLCA , Ulrike TONTSCH-GRUNT , Ralph BRUECKNER , Charlotte REITHER , Lars HERFURTH , Oliver KRAEMER , Heinz STADTMUELLER , Harald ENGELHARDT

IPC分类号： C07D239/48 , C07D401/14 , C07D401/12 , C07D487/08 , A61K31/5377 , A61K45/06 , A61K31/506 , A61K31/505 , A61K31/551 , C07D403/12 , C07D409/14

CPC分类号： C07D239/48 , A61K31/505 , A61K31/506 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/14 , C07D487/08

摘要： The present invention encompasses compounds of general formula (1) wherein R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.

摘要翻译： 本发明包括通式（1）的化合物，其中R 1至R 3如权利要求1中所定义，其适用于治疗以细胞增殖过度或异常为特征的疾病，以及其用于制备具有上述药物组合物的用途提到的属性。

2.

发明申请
2,4-DIAMINO-PYRIMIDINES AS AURORA INHIBITORS 审中-公开
标题翻译： 2,4-二氨基吡啶作为芳族抑制剂

公开(公告)号：US20110251174A1

公开(公告)日：2011-10-13

申请号：US13159787

申请日：2011-06-14

申请人： Stephan Karl ZAHN , Guido BOEHMELT , Andreas MANTOULIDIS , Ulrich REISER , Matthias TREU , Ulrich GUERTLER , Andreas SCHOOP , Flavio SOLCA , Ulrike TONTSCH-GRUNT , Ralph BRUECKNER , Charlotte REITHER , Lars HERFURTH , Oliver KRAEMER , Heinz STADTMUELLER , Harald ENGELHARDT

发明人： Stephan Karl ZAHN , Guido BOEHMELT , Andreas MANTOULIDIS , Ulrich REISER , Matthias TREU , Ulrich GUERTLER , Andreas SCHOOP , Flavio SOLCA , Ulrike TONTSCH-GRUNT , Ralph BRUECKNER , Charlotte REITHER , Lars HERFURTH , Oliver KRAEMER , Heinz STADTMUELLER , Harald ENGELHARDT

IPC分类号： A61K31/506 , A61K31/505 , C07D403/12 , A61K31/551 , C07D413/14 , A61P35/00 , C07D401/14 , C07D401/12 , C07D413/12 , C07D487/08 , C07D409/14 , C07D239/48 , A61K31/5377

CPC分类号： C07D239/48 , A61K31/505 , A61K31/506 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/14 , C07D487/08

摘要： The present invention encompasses compounds of general formula (1) wherein R1 to R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.

摘要翻译： 本发明包括通式（1）的化合物，其中R 1至R 3如权利要求1中所定义，其适用于治疗以细胞增殖过度或异常为特征的疾病，以及其用于制备具有上述药物组合物的用途提到的属性。

3.

发明申请
Pyrimidines as PLK inhibitors 审中-公开
标题翻译：嘧啶类作为PLK抑制剂

公开(公告)号：US20110086842A1

公开(公告)日：2011-04-14

申请号：US12972976

申请日：2010-12-20

申请人： Heinz STADTMUELLER , Harald ENGELHARDT , Martin STEEGMAIER , Anke BAUM , Ulrich GUERTLER , Andreas SCHOOP , Jens Juergen QUANT , Flavio SOLCA , Rudolf HAUPTMANN , Ulrich REISER , Stephan Karl ZAHN , Lars HERFURTH

发明人： Heinz STADTMUELLER , Harald ENGELHARDT , Martin STEEGMAIER , Anke BAUM , Ulrich GUERTLER , Andreas SCHOOP , Jens Juergen QUANT , Flavio SOLCA , Rudolf HAUPTMANN , Ulrich REISER , Stephan Karl ZAHN , Lars HERFURTH

IPC分类号： A61K31/553 , A61K31/506 , A61K31/5355 , A61P35/00 , A61P31/00 , A61P37/00

CPC分类号： C07D239/42 , C07D239/48 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14 , C07D453/02 , C07D471/04 , C07D487/04 , C07D487/08 , C07D491/08 , C07D491/10

摘要： The present invention encompasses compounds of general formula (1), wherein A, W, X, Y, Z, Ra, Rb, Rc, R1 and R3 are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a pharmaceutical composition having the above-mentioned properties.

摘要翻译： 本发明包括通式（1）的化合物，其中A，W，X，Y，Z，Ra，Rb，Rc，R 1和R 3如权利要求1中所定义，其适用于治疗以过量或异常细胞增殖，以及其用于制备具有上述性质的药物组合物的用途。