发明申请
US20130296295A1 BCL-2 SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES
有权
BCL-2治疗癌症和免疫疾病的选择性病毒诱导剂
- 专利标题： BCL-2 SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES
- 专利标题（中）： BCL-2治疗癌症和免疫疾病的选择性病毒诱导剂
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申请号： US13839060申请日： 2013-03-15
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公开(公告)号： US20130296295A1公开(公告)日： 2013-11-07
- 发明人: Milan BRUNCKO , Hong DING , George A. DOHERTY , Steven W. ELMORE , Lisa HASVOLD , Laura HEXAMER , Aaron R. KUNZER , Robert A. MANTEI , William J. MCCLELLAN , Chang H. PARK , Cheol-Min PARK , Andrew M. PETROS , Xiahong SONG , Andrew J. SOUERS , Gerard M. SULLIVAN , Zhi-Fu TAO , Gary T. WANG , Le WANG , Xilu WANG , Michael D. WENDT , Todd M. HANSEN
- 申请人： ABBVIE INC.
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D295/13 ; A61K45/06 ; C07D401/12 ; C07D405/12 ; C07D487/04 ; C07D309/08 ; A61K31/5377
摘要：
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.
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