- 专利标题: TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
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申请号: US13857665申请日: 2013-04-05
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公开(公告)号: US20130296378A1公开(公告)日: 2013-11-07
- 发明人: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Prezewloka , Shijie Zhang , Dinesh U. Chimmanamada , Kevin Paul Foley , Zhenjian Du , Hao Li , David James , Howard P. Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- 申请人: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Prezewloka , Shijie Zhang , Dinesh U. Chimmanamada , Kevin Paul Foley , Zhenjian Du , Hao Li , David James , Howard P. Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- 申请人地址: US MA Lexington
- 专利权人: SYNTA PHARMACEUTICALS CORP.
- 当前专利权人: SYNTA PHARMACEUTICALS CORP.
- 当前专利权人地址: US MA Lexington
- 主分类号: C07D401/04
- IPC分类号: C07D401/04 ; A61K45/06 ; A61K31/4439 ; C07D401/14
摘要:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
公开/授权文献
- US08835464B2 Triazole compounds that modulate HSP90 activity 公开/授权日:2014-09-16
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