发明申请
- 专利标题: Sentinel Lymph Node Marker Capable of Multi-Mode Imaging
- 专利标题(中): 哨兵淋巴结标记能够进行多模式成像
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申请号: US13816931申请日: 2011-08-16
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公开(公告)号: US20130309169A1公开(公告)日: 2013-11-21
- 发明人: Seok Ki Kim , Se Hun Kang , Seo Il Kim , Young Sang Kim , Nam Suk Baek , Jin Hee Noh
- 申请人: Seok Ki Kim , Se Hun Kang , Seo Il Kim , Young Sang Kim , Nam Suk Baek , Jin Hee Noh
- 申请人地址: KR Goyang-si
- 专利权人: NATIONAL CANCER CENTER
- 当前专利权人: NATIONAL CANCER CENTER
- 当前专利权人地址: KR Goyang-si
- 优先权: KR10-2010-0078330 20100813
- 国际申请: PCT/KR2011/005994 WO 20110816
- 主分类号: A61K51/08
- IPC分类号: A61K51/08
摘要:
The present invention relates to a sentinel lymph node marker comprising an albumin; a radioactive isotope and/or near infrared dye which is bound to the albumin; and a visible dye which is bound to the albumin, a preparation method thereof, a kit for multimode imaging of a sentinel lymph node to prepare the sentinel lymph node marker, and a method for multimode imaging of a sentinel lymph node using the same. The sentinel lymph node marker of the invention remains in the sentinel lymph node for a long period of time and allows for multimode imaging of the sentinel lymph node. Thus, using this marker the sentinel lymph node can be accurately identified in vivo by near infrared imaging and/or gamma imaging without incision of skin, and the location of the identified sentinel lymph node can be precisely identified with the naked eye during a surgical operation of removing the identified sentinel lymph node.
公开/授权文献
- US10881750B2 Sentinel lymph node marker capable of multi-mode imaging 公开/授权日:2021-01-05
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