发明申请
US20130325108A1 BIODEGRADABLE MEDICAL IMPLANTS, POLYMER COMPOSITIONS AND METHODS OF USE
审中-公开
生物可降解医用植入物,聚合物组合物和使用方法
- 专利标题: BIODEGRADABLE MEDICAL IMPLANTS, POLYMER COMPOSITIONS AND METHODS OF USE
- 专利标题(中): 生物可降解医用植入物,聚合物组合物和使用方法
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申请号: US13261054申请日: 2010-06-01
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公开(公告)号: US20130325108A1公开(公告)日: 2013-12-05
- 发明人: Mir Imran , Sanjay Patel , Joel Harris
- 申请人: Mir Imran , Sanjay Patel , Joel Harris
- 国际申请: PCT/US10/01609 WO 20100601
- 主分类号: A61L27/14
- IPC分类号: A61L27/14 ; A61F2/04 ; A61F2/82
摘要:
Embodiments of the invention provide compositions comprising bio degradable polymers, medical implants fabricated from these compositions and methods of using such implants. Many embodiments provide medical implants comprising a first polymer backbone having a first rate of biodegradation and a second polymer backbone having a second rate of biodegradation faster than the first rate. In some embodiments, the second backbone is configured to be replaced by a natural tissue layer. The first backbone provides a scaffold for the implant while the second backbone degrades. This scaffold can enhance mechanical properties of the implant including various aspects of mechanical strength such as tensile, bending, hoop and yield strength; and elasticity. The scaffold also serves to maintain a minimum level of structural support of the implant during the period of degradation of the second backbone or for the entire life of the implant so that the implant does not mechanically fail.
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