发明申请
- 专利标题: ANTI-NGF ANTIBODIES AND THEIR USE
- 专利标题(中): 抗NGF抗体及其使用
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申请号: US13817721申请日: 2011-08-19
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公开(公告)号: US20130330348A1公开(公告)日: 2013-12-12
- 发明人: Susan E. Lacy , Jeffrey A. Barbon , Meha Chhaya , Emma Fung , Charles W. Hutchins , Diane M. Lang , Eve H. Barlow , Mary Leddy , Ravi Chari
- 申请人: Susan E. Lacy , Jeffrey A. Barbon , Meha Chhaya , Emma Fung , Charles W. Hutchins , Diane M. Lang , Eve H. Barlow , Mary Leddy , Ravi Chari
- 申请人地址: US IL ABBOTT PARK
- 专利权人: ABBOTT LABORATORIES
- 当前专利权人: ABBOTT LABORATORIES
- 当前专利权人地址: US IL ABBOTT PARK
- 国际申请: PCT/US11/48518 WO 20110819
- 主分类号: C07K16/22
- IPC分类号: C07K16/22
摘要:
The present disclosure encompasses NGF binding proteins, specifically to antibodies that are chimeric, CDR grafted and canonized antibodies, and methods of making and uses thereof. The antibodies, or antibody portions, of the disclosure are useful for detecting NGF and for inhibiting NGF activity, e.g., in a mammal subject suffering from a disorder in which NGF activity is detrimental.
公开/授权文献
- US09505829B2 Anti-NGF antibodies and their use 公开/授权日:2016-11-29
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