发明申请
US20130336937A1 CHONDROGENIC DIFFERENTIATION MEDIA AND METHODS FOR INDUCING CHONDROGENIC DIFFERENTIATION OF CELLS
审中-公开
造血分化培养基和诱导细胞成纤维细胞增生的方法
- 专利标题: CHONDROGENIC DIFFERENTIATION MEDIA AND METHODS FOR INDUCING CHONDROGENIC DIFFERENTIATION OF CELLS
- 专利标题(中): 造血分化培养基和诱导细胞成纤维细胞增生的方法
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申请号: US14001523申请日: 2012-03-16
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公开(公告)号: US20130336937A1公开(公告)日: 2013-12-19
- 发明人: Emilie Rederstorff , Corinne Sinquin , Jacqueline Ratiskol , Sylvia Colliec-Jouault , Jérome Guicheux , Pierre Weiss , Christophe Merceron
- 申请人: Emilie Rederstorff , Corinne Sinquin , Jacqueline Ratiskol , Sylvia Colliec-Jouault , Jérome Guicheux , Pierre Weiss , Christophe Merceron
- 申请人地址: FR Paris FR Nantes FR Issy Les Moulineaux
- 专利权人: Institut National de la Sante et de Ia Recherche Medicale,UNIVERSITE DE NANTES,INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER
- 当前专利权人: Institut National de la Sante et de Ia Recherche Medicale,UNIVERSITE DE NANTES,INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER
- 当前专利权人地址: FR Paris FR Nantes FR Issy Les Moulineaux
- 优先权: EP11305306.0 20110318
- 国际申请: PCT/EP2012/054654 WO 20120316
- 主分类号: C12N5/077
- IPC分类号: C12N5/077
摘要:
The invention provides chondrogenic differentiation media comprising chondrogenic growth factors and low-molecular-weight sulfated polysaccharide derivatives of marine native exopolysaccharides (EPS) excreted by mesophilic marine bacteria from deep-sea hydrothermal environments. The invention relates to methods for inducing chondrogenic differentiation in pluripotent or multipotent cells, to cartilage tissues obtained by such methods, and to the use of such cartilage tissues for therapeutic purposes.
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