Invention Application
US20130338138A1 AZETIDINE AND PIPERIDINE COMPOUNDS USEFUL AS PDE10 INHIBITORS
有权
阿司匹林和哌啶化合物作为PDE10抑制剂有用
- Patent Title: AZETIDINE AND PIPERIDINE COMPOUNDS USEFUL AS PDE10 INHIBITORS
- Patent Title (中): 阿司匹林和哌啶化合物作为PDE10抑制剂有用
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Application No.: US13917699Application Date: 2013-06-14
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Publication No.: US20130338138A1Publication Date: 2013-12-19
- Inventor: Jennifer R. Allen , Jian J. Chen , Michael J. Frohn , Matthew R. Kaller , Qingyian Liu , Thomas T. Nguyen , Alexander J. Pickrell , Wenyuan Qian , Robert M. Rzasa , Wenge Zhong
- Applicant: AMGEN INC.
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D471/04 ; A61K31/517 ; A61K31/497 ; A61K45/06

Abstract:
Azetidine and piperidine compounds of formula (I): as defined in the specification, compositions containing them, and processes for preparing such compounds and intermediates thereof. Provided herein also are methods of treating cognitive disorders or diseases treatable by inhibition of PDE10, such as Huntington's Disease, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
Public/Granted literature
- US08691986B2 Azetidine and piperidine compounds useful as PDE10 inhibitors Public/Granted day:2014-04-08
Information query