发明申请
US20130338138A1 AZETIDINE AND PIPERIDINE COMPOUNDS USEFUL AS PDE10 INHIBITORS
有权
阿司匹林和哌啶化合物作为PDE10抑制剂有用
- 专利标题: AZETIDINE AND PIPERIDINE COMPOUNDS USEFUL AS PDE10 INHIBITORS
- 专利标题(中): 阿司匹林和哌啶化合物作为PDE10抑制剂有用
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申请号: US13917699申请日: 2013-06-14
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公开(公告)号: US20130338138A1公开(公告)日: 2013-12-19
- 发明人: Jennifer R. Allen , Jian J. Chen , Michael J. Frohn , Matthew R. Kaller , Qingyian Liu , Thomas T. Nguyen , Alexander J. Pickrell , Wenyuan Qian , Robert M. Rzasa , Wenge Zhong
- 申请人: AMGEN INC.
- 主分类号: C07D401/14
- IPC分类号: C07D401/14 ; C07D471/04 ; A61K31/517 ; A61K31/497 ; A61K45/06
摘要:
Azetidine and piperidine compounds of formula (I): as defined in the specification, compositions containing them, and processes for preparing such compounds and intermediates thereof. Provided herein also are methods of treating cognitive disorders or diseases treatable by inhibition of PDE10, such as Huntington's Disease, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
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