A mechanism is described for facilitating real-time customization of messages to be transmitted between computing systems according to one embodiment of the invention. A method of embodiments of the invention includes receiving a notification relating to call made to a first computing device from a second computing device. The call may remain unanswered. The method may further include accessing a first data relating to a current status of the first computing device, analyzing the first data, and customizing, in real-time, a response based on the analyzed first data. The method may further include transmitting the customized response to the second computing device, in response to the unanswered call.