发明申请
- 专利标题: PARTICLE COMPOSITION AND PHARMACEUTICAL COMPOSITION USING PARTICLE COMPOSITION
- 专利标题(中): 颗粒组合物和使用颗粒组合物的药物组合物
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申请号: US13979546申请日: 2012-01-16
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公开(公告)号: US20140017328A1公开(公告)日: 2014-01-16
- 发明人: Kazunori Kataoka , Ronald James Christie , Nobuhiro Nishiyama , Kanjiro Miyata , Shigeto Fukushima , Yu Matsumoto , Takahiro Nomoto , Yasuki Kato
- 申请人: Kazunori Kataoka , Ronald James Christie , Nobuhiro Nishiyama , Kanjiro Miyata , Shigeto Fukushima , Yu Matsumoto , Takahiro Nomoto , Yasuki Kato
- 申请人地址: JP Chiba JP Tokyo
- 专利权人: NANOCARRIER CO., LTD.,THE UNIVERSITY OF TOKYO
- 当前专利权人: NANOCARRIER CO., LTD.,THE UNIVERSITY OF TOKYO
- 当前专利权人地址: JP Chiba JP Tokyo
- 优先权: JP2011-006318 20110114
- 国际申请: PCT/JP2012/050683 WO 20120116
- 主分类号: A61K9/50
- IPC分类号: A61K9/50 ; A61K38/19 ; A61K31/713
摘要:
A composition of matter for use in encapsulating a drug is expressed by formula (1) or formula (2): wherein R1 and R2 are each independently a hydrogen atom or a substituted or unsubstituted, linear or branched alkyl group having 1 to 12 carbon atoms; A is a hydrophilic polymer chain; L1 and L3 are each a linking group; B is a cation-containing group; R3 is a side chain of an amino acid; z is an integer of 5 to 500; x is an integer of 40% or more of z; y is 0 or a positive integer; z-x-y is 0 or a positive integer; p is an integer of 1 to 10; and q is an integer of 1 to 10.
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