公开(公告)号：US20140017328A1

公开(公告)日：2014-01-16

申请号：US13979546

申请日：2012-01-16

申请人： Kazunori Kataoka ,  Ronald James Christie ,  Nobuhiro Nishiyama ,  Kanjiro Miyata ,  Shigeto Fukushima ,  Yu Matsumoto ,  Takahiro Nomoto ,  Yasuki Kato

发明人： Kazunori Kataoka ,  Ronald James Christie ,  Nobuhiro Nishiyama ,  Kanjiro Miyata ,  Shigeto Fukushima ,  Yu Matsumoto ,  Takahiro Nomoto ,  Yasuki Kato

IPC分类号： A61K9/50 ,  A61K38/19 ,  A61K31/713

CPC分类号： A61K9/5031 ,  A61K9/107 ,  A61K31/711 ,  A61K31/713 ,  A61K38/193 ,  A61K47/60 ,  A61K47/6455

摘要： A composition of matter for use in encapsulating a drug is expressed by formula (1) or formula (2): wherein R1 and R2 are each independently a hydrogen atom or a substituted or unsubstituted, linear or branched alkyl group having 1 to 12 carbon atoms; A is a hydrophilic polymer chain; L1 and L3 are each a linking group; B is a cation-containing group; R3 is a side chain of an amino acid; z is an integer of 5 to 500; x is an integer of 40% or more of z; y is 0 or a positive integer; z-x-y is 0 or a positive integer; p is an integer of 1 to 10; and q is an integer of 1 to 10.

摘要翻译： 用于包封药物的物质组合物由式（1）或式（2）表示：其中R 1和R 2各自独立地为氢原子或具有1至12个碳原子的取代或未取代的直链或支链烷基 ; A是亲水性聚合物链; L1和L3各自是连接基团; B是含阳离子基团; R3是氨基酸的侧链; z为5〜500的整数。 x是z的40％以上的整数; y为0或正整数; z-x-y为0或正整数; p为1〜10的整数。 q为1〜10的整数。

公开(公告)号：US09278075B2

公开(公告)日：2016-03-08

申请号：US13979546

申请日：2012-01-16

申请人： Kazunori Kataoka ,  Ronald James Christie ,  Nobuhiro Nishiyama ,  Kanjiro Miyata ,  Shigeto Fukushima ,  Yu Matsumoto ,  Takahiro Nomoto ,  Yasuki Kato

发明人： Kazunori Kataoka ,  Ronald James Christie ,  Nobuhiro Nishiyama ,  Kanjiro Miyata ,  Shigeto Fukushima ,  Yu Matsumoto ,  Takahiro Nomoto ,  Yasuki Kato

IPC分类号： A61K9/50 ,  A61K38/19 ,  A61K31/713 ,  A61K31/711 ,  A61K9/107 ,  A61K47/48

CPC分类号： A61K9/5031 ,  A61K9/107 ,  A61K31/711 ,  A61K31/713 ,  A61K38/193 ,  A61K47/60 ,  A61K47/6455

摘要： A composition of matter for use in encapsulating a drug is expressed by formula (1) or formula (2): wherein R1 and R2 are each independently a hydrogen atom or a substituted or unsubstituted, linear or branched alkyl group having 1 to 12 carbon atoms; A is a hydrophilic polymer chain; L1 and L3 are each a linking group; B is a cation-containing group; R3 is a side chain of an amino acid; z is an integer of 5 to 500; x is an integer of 40% or more of z; y is 0 or a positive integer; z-x-y is 0 or a positive integer; p is an integer of 1 to 10; and q is an integer of 1 to 10.

摘要翻译： 用于包封药物的物质组合物由式（1）或式（2）表示：其中R 1和R 2各自独立地为氢原子或具有1至12个碳原子的取代或未取代的直链或支链烷基 ; A是亲水性聚合物链; L1和L3各自是连接基团; B是含阳离子基团; R3是氨基酸的侧链; z为5〜500的整数。 x是z的40％以上的整数; y为0或正整数; z-x-y为0或正整数; p为1〜10的整数。 q为1〜10的整数。