发明申请
US20140024542A1 METHODS AND COMPOSITIONS FOR ENRICHMENT OF TARGET POLYNUCLEOTIDES
审中-公开
用于增强目标多核苷酸的方法和组合物
- 专利标题: METHODS AND COMPOSITIONS FOR ENRICHMENT OF TARGET POLYNUCLEOTIDES
- 专利标题(中): 用于增强目标多核苷酸的方法和组合物
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申请号: US13551590申请日: 2012-07-17
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公开(公告)号: US20140024542A1公开(公告)日: 2014-01-23
- 发明人: Hunter Richards , Eric Evans , Balaji Srinivasan , Subramaniam Srinivasan , Clement Chu
- 申请人: Hunter Richards , Eric Evans , Balaji Srinivasan , Subramaniam Srinivasan , Clement Chu
- 申请人地址: US CA South San Francisco
- 专利权人: Counsyl, Inc.
- 当前专利权人: Counsyl, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: C40B30/04
- IPC分类号: C40B30/04 ; C40B50/06
摘要:
The invention provides methods, apparatuses, and compositions for high-throughput amplification sequencing of specific target sequences in one or more samples. In some aspects, barcode-tagged polynucleotides are sequenced simultaneously and sample sources are identified on the basis of barcode sequences. In some aspects, sequencing data are used to determine one or more genotypes at one or more loci comprising a causal genetic variant.
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