发明申请
- 专利标题： CULTURE MEDIUM AND METHOD FOR OBTAINING A POPULATION OF TOLEROGENIC DENDRITIC CELLS
- 专利标题（中）： 文化媒介和获取嗜酸粒细胞群体的方法
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申请号： US14009999申请日： 2012-04-05
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公开(公告)号： US20140037607A1公开(公告)日： 2014-02-06
- 发明人: Hakim Hocini , Renato Monteiro , Hicham Bouhlal , Agnes Lehuen , Julien Diana
- 申请人： Hakim Hocini , Renato Monteiro , Hicham Bouhlal , Agnes Lehuen , Julien Diana
- 申请人地址： FR Paris
- 专利权人： Institut National de la Sante et de la Recherche Medicale(INSERM)
- 当前专利权人： Institut National de la Sante et de la Recherche Medicale(INSERM)
- 当前专利权人地址： FR Paris
- 优先权： EP11305412.6 20110408
- 国际申请： PCT/EP12/56365 WO 20120405
- 主分类号： C12N5/0784
- IPC分类号： C12N5/0784
摘要：
The present invention relates to a culture medium suitable for inducing dendritic cell differentiation comprising an effective amount of secretory immunoglobulins A (SIgA) and also to a method for obtaining a population of tolerogenic dendritic cells from cells, in particular monocytes. The present invention relates to uses of tolerogenic dendritic cells thus obtained in therapy and in induction of transplant tolerance.
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