发明申请
US20140046197A1 CLASSIFICATION OF TUMOR TISSUE WITH A PERSONALIZED THRESHOLD
有权
具有个性化THRESHOLD的肿瘤组织分类
- 专利标题: CLASSIFICATION OF TUMOR TISSUE WITH A PERSONALIZED THRESHOLD
- 专利标题(中): 具有个性化THRESHOLD的肿瘤组织分类
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申请号: US14112555申请日: 2012-04-10
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公开(公告)号: US20140046197A1公开(公告)日: 2014-02-13
- 发明人: Gerhardus Wilhelmus Lucassen , Bernardus Hendrikus Wilhelmus Hendriks , Rami Nachabe
- 申请人: Gerhardus Wilhelmus Lucassen , Bernardus Hendrikus Wilhelmus Hendriks , Rami Nachabe
- 申请人地址: NL EINDHOVEN
- 专利权人: KONINKLIJKE PHILIPS N.V.
- 当前专利权人: KONINKLIJKE PHILIPS N.V.
- 当前专利权人地址: NL EINDHOVEN
- 优先权: EP11162815.2 20110418
- 国际申请: PCT/IB12/51742 WO 20120410
- 主分类号: A61B5/00
- IPC分类号: A61B5/00 ; A61B1/00
摘要:
The present invention deals with discrimination of malignant tissue from normal and benign tissue in a single patient on the basis of optical spectroscopic measurements. Starting from spectroscopic measurements in normal tissue, reference values are obtained for the normal class. With spectroscopic measurements in other tissues data points can be assigned to new class(es) when the spectral characteristics fall outside a threshold defining the reference class. Thresholds between different classes can also be defined. Finding (the transition to) malignant tissue is based on comparing the spectroscopic values to the classification threshold discriminating normal and benign versus malignant tissue. Thus, the basis of normal spectroscopic measurements is tuned to the individual patient characteristic. Discriminating the normal plus benign and malignant from that reference is more efficient compared to the reference of the all patient database.