Invention Application
- Patent Title: 2-AMINO-4-ARYLTHIAZOLE COMPOUNDS AS TRPA1 ANTAGONISTS
- Patent Title (中): 2-氨基-4-氰基噻唑化合物作为TRPA1拮抗剂
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Application No.: US14058536Application Date: 2013-10-21
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Publication No.: US20140051667A1Publication Date: 2014-02-20
- Inventor: Sukeerthi Kumar , Abraham Thomas , Sachin Sundarlal Chaudhari , Bipin Parsottam Kansagra , Venkata Ramana Yemireddy , Neelima Khairatkar-Joshi , Indranil Mukhopadhyay , Girish Gudi
- Applicant: Glenmark Pharmaceuticals, S.A.
- Applicant Address: CH La Chaux-de-Fonds
- Assignee: Glenmark Pharmaceuticals, S.A.
- Current Assignee: Glenmark Pharmaceuticals, S.A.
- Current Assignee Address: CH La Chaux-de-Fonds
- Priority: IN3451/MUM/2010 20101220; IN748/MUM/2011 20110316; IN1569/MUM/2011 20110525; IN2741/MUM/2011 20110928
- Main IPC: C07F9/6561
- IPC: C07F9/6561
Abstract:
The present invention is related to 2-amino-4-arylthiazole derivatives as TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.
Public/Granted literature
- US09073955B2 2-amino-4-arylthiazole compounds as TRPA1 antagonists Public/Granted day:2015-07-07
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