发明申请
- 专利标题： Antigenic GM-CSF Peptides and Antibodies to GM-CSF
- 专利标题（中）： 抗原GM-CSF肽和GM-CSF抗体
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申请号： US14091028申请日： 2013-11-26
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公开(公告)号： US20140086928A1公开(公告)日： 2014-03-27
- 发明人: Philip M. Sass , Nicholas C. Nicolaides , Luigi Grasso , Jian Li , Qimin Chao , Eric Routhier , Wolfgang Ebel
- 申请人： Philip M. Sass , Nicholas C. Nicolaides , Luigi Grasso , Jian Li , Qimin Chao , Eric Routhier , Wolfgang Ebel
- 申请人地址： US PA Exton
- 专利权人： MORPHOTEK, INC.
- 当前专利权人： MORPHOTEK, INC.
- 当前专利权人地址： US PA Exton
- 主分类号： C07K16/24
- IPC分类号： C07K16/24
摘要：
Hybridoma lines that secrete human monoclonal antibodies with high binding specificity and biological activity, particularly neutralizing activity against granulocyte-macrophage colony stimulating factor, and methods of generating the hybridoma lines are provided. Target antigens and epitopes are also provided. The antibodies may be used in therapeutic methods, for example in the treatment of cancer, infectious disease, or autoimmune disease.
公开/授权文献
- US09422367B2 Antigenic GM-CSF peptides and antibodies to GM-CSF 公开/授权日：2016-08-23
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