发明申请
US20140113905A1 INHIBITION OF PHOSPHORYLATION OF PRAS40, GSK3-BETA OR P70S6K1 AS A MARKER FOR TOR KINASE INHIBITORY ACTIVITY
有权
PRAS40，GSK3-BETA或P70S6K1的磷酸化抑制作为诱导剂抑制活性的标记
- 专利标题： INHIBITION OF PHOSPHORYLATION OF PRAS40, GSK3-BETA OR P70S6K1 AS A MARKER FOR TOR KINASE INHIBITORY ACTIVITY
- 专利标题（中）： PRAS40，GSK3-BETA或P70S6K1的磷酸化抑制作为诱导剂抑制活性的标记
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申请号： US14055995申请日： 2013-10-17
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公开(公告)号： US20140113905A1公开(公告)日： 2014-04-24
- 发明人: Weiming Xu , Deborah Mortensen , Shuichan Xu , Kimberly Elizabeth Fultz
- 申请人： SIGNAL PHARMACEUTICALS, LLC
- 申请人地址： US CA San Diego
- 专利权人： SIGNAL PHARMACEUTICALS, LLC
- 当前专利权人： SIGNAL PHARMACEUTICALS, LLC
- 当前专利权人地址： US CA San Diego
- 主分类号： A61K31/4985
- IPC分类号： A61K31/4985 ; G01N33/574 ; G01N33/50
摘要：
Provided herein are methods for treating a cancer treatable by inhibition of phosphorylation of PRAS40, GSK3β or p70S6K1, comprising administering an effective amount of a TOR kinase inhibitor to a patient having a cancer treatable by inhibition of phosphorylation of PRAS40, GSK3β or p70S6K1.
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