发明申请
US20140127325A1 Compositions and Method for Inhibiting Hepcidin Antimicrobial Peptide (HAMP) or HAMP-Related Gene Expression
有权
抑制Hepcidin抗菌肽(HAMP)或HAMP相关基因表达的组合物和方法
- 专利标题: Compositions and Method for Inhibiting Hepcidin Antimicrobial Peptide (HAMP) or HAMP-Related Gene Expression
- 专利标题(中): 抑制Hepcidin抗菌肽(HAMP)或HAMP相关基因表达的组合物和方法
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申请号: US14118489申请日: 2012-06-21
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公开(公告)号: US20140127325A1公开(公告)日: 2014-05-08
- 发明人: Brian Bettencourt , Akin Akinc , Alfica Sehgal , Don Foster , Stuart Milstein , Satyanarayana Kuchimanchi , Martin A. Maier , Klaus Charisse , Kallanthottathil Rajeev
- 申请人: Brian Bettencourt , Akin Akinc , Alfica Sehgal , Don Foster , Stuart Milstein , Satyanarayana Kuchimanchi , Martin A. Maier , Klaus Charisse , Kallanthottathil Rajeev
- 国际申请: PCT/US2012/043603 WO 20120621
- 主分类号: C12N15/113
- IPC分类号: C12N15/113 ; A61K47/48 ; A61K33/26 ; A61K31/7105
摘要:
The invention relates to lipid formulated double-stranded ribonucleic acid (dsRNA) targeting a hepcidin antimicrobial peptide (HAMP) and/or HAMP-related gene, and methods of using the dsRNA to inhibit expression of HAMP and/or HAMP-related genes.
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