发明申请
US20140127803A1 iPS CELL HAVING DIFFERENTIATION PROPENSITY FOR CORNEAL EPITHELIUM
审中-公开
iPS细胞具有对角膜上皮的差异性特征
- 专利标题： iPS CELL HAVING DIFFERENTIATION PROPENSITY FOR CORNEAL EPITHELIUM
- 专利标题（中）： iPS细胞具有对角膜上皮的差异性特征
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申请号： US14112572申请日： 2012-04-20
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公开(公告)号： US20140127803A1公开(公告)日： 2014-05-08
- 发明人: Ryuhei Hayashi , Kohji Nishida
- 申请人： Ryuhei Hayashi , Kohji Nishida
- 申请人地址： JP Osaka
- 专利权人： OSAKA UNIVERISTY
- 当前专利权人： OSAKA UNIVERISTY
- 当前专利权人地址： JP Osaka
- 优先权： JP2011-093846 20110420
- 国际申请： PCT/JP2012/060667 WO 20120420
- 主分类号： C12N5/071
- IPC分类号： C12N5/071
摘要：
A major object of the present invention is to provide a method for inducing cell differentiation into corneal epithelial stem cells and/or corneal epithelial cells, for the easy production of a corneal epithelial cell sheet having superior safety in view of the possibility of vascularization and the like occurring. A method for inducing differentiation of a pluripotent stem cell into a corneal epithelial stem cell and/or a corneal epithelial cell, the method comprising the step of culturing a pluripotent stem cell in the presence of a stromal cell or an amnion-derived factor.
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