发明申请
US20140128318A1 NOVEL OXYNTOMODULIN DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR TREATING OBESITY COMPRISING THE SAME
有权
用于治疗包含其的肥胖症的新型氧化色氨酸衍生物和药物组合物
- 专利标题： NOVEL OXYNTOMODULIN DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR TREATING OBESITY COMPRISING THE SAME
- 专利标题（中）： 用于治疗包含其的肥胖症的新型氧化色氨酸衍生物和药物组合物
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申请号： US14124969申请日： 2012-06-07
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公开(公告)号： US20140128318A1公开(公告)日： 2014-05-08
- 发明人: Sung Youb Jung , Myung Hyun Jang , Ling Ai Shen , Young Kyung Park , Young Jin Park , Se Chang Kwon
- 申请人： Sung Youb Jung , Myung Hyun Jang , Ling Ai Shen , Young Kyung Park , Young Jin Park , Se Chang Kwon
- 申请人地址： KR Hwaseong-si
- 专利权人： Hanmi Science Co., Ltd.
- 当前专利权人： Hanmi Science Co., Ltd.
- 当前专利权人地址： KR Hwaseong-si
- 优先权： KR10-2011-0056472 20110610
- 国际申请： PCT/KR2012/004494 WO 20120607
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; A61K45/06 ; A61K38/17
摘要：
The present invention relates to a novel peptide showing more excellent activities on a glucagon like peptide-1 receptor and a glucagon receptor than native oxyntomodulin, and a composition for the prevention or treatment of obesity comprising the peptide as an active ingredient. Unlike native oxyntomodulin, the novel peptide of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis with reduced side-effects, and also shows excellent receptor-activating effects. Thus, it can be widely used in the treatment of obesity with safety and efficacy.
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