发明申请
- 专利标题: METHODS AND KITS FOR DIAGNOSING SJOGREN'S SYNDROME
- 专利标题(中): 用于诊断SJOGREN'S SYNDROME的方法和工具
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申请号: US14078020申请日: 2013-11-12
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公开(公告)号: US20140134644A1公开(公告)日: 2014-05-15
- 发明人: Denise L. FAUSTMAN
- 申请人: The General Hospital Corporation
- 申请人地址: US MA Boston
- 专利权人: The General Hospital Corporation
- 当前专利权人: The General Hospital Corporation
- 当前专利权人地址: US MA Boston
- 主分类号: G01N33/543
- IPC分类号: G01N33/543
摘要:
The invention features methods and kits for determining the presence of, or a predisposition to develop, Sjögren's syndrome in humans. The invention features methods to detect changes in the levels of one or more LMP-2 protein isoforms, in particular phosphorylated isoforms of LMP-2, and to detect changes in cellular protein phosphorylation and ubiquitination in samples from Sjögren's patients.
公开/授权文献
- US08969015B2 Methods and kits for diagnosing Sjögren's syndrome 公开/授权日:2015-03-03