Invention Application
- Patent Title: CELL CULTURE IMPROVEMENTS
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Application No.: US14157460Application Date: 2014-01-16
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Publication No.: US20140134675A1Publication Date: 2014-05-15
- Inventor: Itzcoatl A. Pla , Joseph C. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , Yu-Hsiang David Chang , Thomas Seewoester
- Applicant: Itzcoatl A. Pla , Thomas Seewoester , Yu-Hsiang David Chang , James McIntire , David F. Bruton , Nichole A. Roy , Christof Schulz , John C. Fann , Joseph C. Matuck
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: C07K16/24
- IPC: C07K16/24
Abstract:
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Public/Granted literature
- US09234032B2 Fed-batch methods for producing adalimumab Public/Granted day:2016-01-12
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