发明申请
- 专利标题： AMINOPYRIMIDINES AS SYK INHIBITORS
- 专利标题（中）： 氨基嘧啶作为SYK抑制剂
-
申请号： US14116207申请日： 2012-05-04
-
公开(公告)号： US20140148474A1公开(公告)日： 2014-05-29
- 发明人: Michael D. Altman , Kaleen Konrad Childers , Maria Emilia Di Francesco , John Michael Ellis , Christian Fischer , Jonathan Grimm , Andrew M. Haidle , Solomon D. Kattar , Alan B. Northrup , Ryan D. Otte , Alessia Petrocchi , Adam J. Schell , Hua Zhou
- 申请人： Michael D. Altman , Kaleen Konrad Childers , Maria Emilia Di Francesco , John Michael Ellis , Christian Fischer , Jonathan Grimm , Andrew M. Haidle , Solomon D. Kattar , Alan B. Northrup , Ryan D. Otte , Alessia Petrocchi , Adam J. Schell , Hua Zhou
- 国际申请： PCT/US12/36423 WO 20120504
- 主分类号： C07D417/12
- IPC分类号： C07D417/12 ; C07D417/14
摘要：
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis and cancer.
公开/授权文献
- US09290490B2 Aminopyrimidines as Syk inhibitors 公开/授权日：2016-03-22
信息查询
