发明申请
US20140155371A1 MULTICOMPONENT CRYSTALLINE SYSTEM OF EZETIMIBE AND PROLINE
审中-公开
EZETIMIBE和PROLINE的多功能晶体系统
- 专利标题: MULTICOMPONENT CRYSTALLINE SYSTEM OF EZETIMIBE AND PROLINE
- 专利标题(中): EZETIMIBE和PROLINE的多功能晶体系统
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申请号: US14234158申请日: 2012-07-24
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公开(公告)号: US20140155371A1公开(公告)日: 2014-06-05
- 发明人: Andreas Hafner , Tobias Hintermann , Martin Szelagiewicz , Bernd Siebenhaar , Fritz Blatter
- 申请人: Andreas Hafner , Tobias Hintermann , Martin Szelagiewicz , Bernd Siebenhaar , Fritz Blatter
- 申请人地址: DE Ludwigshafen
- 专利权人: BASF SE
- 当前专利权人: BASF SE
- 当前专利权人地址: DE Ludwigshafen
- 优先权: EP11175340.6 20110726
- 国际申请: PCT/IB12/53751 WO 20120724
- 主分类号: C07D205/08
- IPC分类号: C07D205/08
摘要:
Provided is a crystalline composition comprising a mixture of a compound of formula 1 (Ezetimibe) and proline or proline derivatives, or a hydrate/solvate thereof, as well as a process for obtaining the same. And a process for the purification of Ezetimibe is also disclosed.