发明申请
- 专利标题: PROPHYLACTIC OR THERAPEUTIC AGENT FOR ORAL DISEASES
- 专利标题(中): 用于口腔疾病的预防或治疗药物
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申请号: US14236849申请日: 2012-08-03
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公开(公告)号: US20140178313A1公开(公告)日: 2014-06-26
- 发明人: Takekazu Okumura , Tomohiko Terai , Masumi Nakao , Kimiyuki Kaneko , Masahiko Ito , Kouji Miyazaki , Kazuaki Yamaji , Kaoru Tochiya , Nobuhiro Hanada , Susumu Imai , Yoshiaki Nomura , Shunsuke Baba
- 申请人: Takekazu Okumura , Tomohiko Terai , Masumi Nakao , Kimiyuki Kaneko , Masahiko Ito , Kouji Miyazaki , Kazuaki Yamaji , Kaoru Tochiya , Nobuhiro Hanada , Susumu Imai , Yoshiaki Nomura , Shunsuke Baba
- 申请人地址: JP Minato-ku, Tokyo
- 专利权人: KABUSHIKI KAISHA YAKULT HONSHA
- 当前专利权人: KABUSHIKI KAISHA YAKULT HONSHA
- 当前专利权人地址: JP Minato-ku, Tokyo
- 优先权: JP2011-171891 20110805
- 国际申请: PCT/JP12/69916 WO 20120803
- 主分类号: A61K8/99
- IPC分类号: A61K8/99 ; C12Q1/68 ; A61Q11/00
摘要:
Provided is a novel lactic acid bacterium strain which is capable of suppressing production of volatile sulfur compounds by oral bacteria, has no cariogenicity and no causative role in infective endocarditis, and is safe in an oral cavity, and provided is an agent for preventing, improving and/or treating oral diseases and discomforts by use of the bacterial strain.An agent for preventing and/or treating an oral disease, containing, as an active ingredient, at least one lactic acid bacterium selected from Lactobacillus crispatus, Lactobacillus fermentum, Lactobacillus gasseri, and Streptococcus mitis and having all of the following properties (1) to (6): (1) having no ability to produce a volatile sulfur compound (VSC); (2) having no ability to produce water-insoluble glucan; (3) having adhesiveness to a tooth surface and/or an oral cell; (4) having a growth inhibitory effect on a bad breath-causing bacterium and/or a periodontal pathogen; (5) having no causative role in infective endocarditis; and (6) having no cariogenicity.
公开/授权文献
- US09730883B2 Prophylactic or therapeutic agent for oral diseases 公开/授权日:2017-08-15
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