发明申请
- 专利标题： ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)
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申请号： US14261063申请日： 2014-04-24
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公开(公告)号： US20140228557A1公开(公告)日： 2014-08-14
- 发明人: Simon Mark Jackson , Nigel Pelham Clinton Walker , Derek Evan Piper , Bei Shan , Wenyan Shen , Joyce Chi Yee Chan , Chadwick Terence King , Randal Robert Ketchem , Christopher Mehlin , Teresa Arazas Carabeo , Qiong Cao
- 申请人： Amgen, Inc.
- 申请人地址： US CA Thousand Oaks
- 专利权人： Amgen, Inc.
- 当前专利权人： Amgen, Inc.
- 当前专利权人地址： US CA Thousand Oaks
- 主分类号： C12N15/113
- IPC分类号： C12N15/113
摘要：
Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
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