发明申请
- 专利标题: CRISPR-BASED GENOME MODIFICATION AND REGULATION
- 专利标题(中): 基于CRISPR的基因改变和调控
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申请号: US14213895申请日: 2014-03-14
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公开(公告)号: US20140273230A1公开(公告)日: 2014-09-18
- 发明人: Fuqiang Chen , Gregory Davis
- 申请人: Fuqiang Chen , Gregory Davis
- 申请人地址: US MO St. Louis
- 专利权人: SIGMA-ALDRICH CO., LLC
- 当前专利权人: SIGMA-ALDRICH CO., LLC
- 当前专利权人地址: US MO St. Louis
- 主分类号: C12N15/85
- IPC分类号: C12N15/85
摘要:
The present invention provides methods for modifying chromosomal sequences. In particular, methods are provided for using RNA-guided endonucleases or modified RNA-guided endonucleases to modify targeted chromosomal sequences.
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