Invention Application
US20140286947A1 PREDICTING PROGRESSION TO ADVANCED AGE-RELATED MACULAR DEGENERATION USING A POLYGENIC SCORE
审中-公开
使用多基因分数预测进展的与年龄相关的年龄变异
- Patent Title: PREDICTING PROGRESSION TO ADVANCED AGE-RELATED MACULAR DEGENERATION USING A POLYGENIC SCORE
- Patent Title (中): 使用多基因分数预测进展的与年龄相关的年龄变异
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Application No.: US13999496Application Date: 2014-03-04
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Publication No.: US20140286947A1Publication Date: 2014-09-25
- Inventor: Timothy W. Behrens , Robert Royal Graham
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention relates to methods for identifying individuals with intermediate age-related macular degeneration (AMD) who possess a greater risk of progression to advanced AMD, using a polygenic score calculated based on the results of genome-wide gene association studies, using thousands of single-nucleotide polymorphisms (SNPs).
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