发明申请
- 专利标题: COMPOUNDS USEFUL FOR TREATING AIDS
- 专利标题(中): 用于治疗艾滋病的化合物
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申请号: US14256334申请日: 2014-04-18
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公开(公告)号: US20140288120A1公开(公告)日: 2014-09-25
- 发明人: Jamal TAZI , Florence MAHUTEAU , Romain NAJMAN , Didier SCHERRER , Noelie CAMPOS , Aude GARCEL
- 申请人: SOCIETE SPLICOS , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , INSTITUT CURIE , UNIVERSITE MONTPELLIER 2
- 申请人地址: FR Montpellier FR Paris FR Paris FR Montpellier
- 专利权人: SOCIETE SPLICOS,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,INSTITUT CURIE,UNIVERSITE MONTPELLIER 2
- 当前专利权人: SOCIETE SPLICOS,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,INSTITUT CURIE,UNIVERSITE MONTPELLIER 2
- 当前专利权人地址: FR Montpellier FR Paris FR Paris FR Montpellier
- 优先权: EP09162630.9 20090612; EP09305540.8 20090612
- 主分类号: C07D401/12
- IPC分类号: C07D401/12
摘要:
A compound having the following formula or a pharmaceutically acceptable salt thereof: where: R″ is a hydrogen atom or a (C1-C4)alkyl group; n′ is 1 or 2; n is 1, 2, or 3; R independently represents a hydrogen atom, a halogen atom, or a group selected from a (C1-C3)alkyl group, a —CN group, a hydroxyl group, a —NR1R2 group, a —COOR1 group, a (C1-C3)fluoroalkyl group, a —NO2 group, a (C1-C3)fluoroalkoxy, and a (C1-C4)alkoxy group; R′ is a hydrogen atom, a halogen atom, or a group selected from a (C1-C3)alkyl group, a —COOR1 group, a —NO2 group, a —NR1R2 group, a (C1-C4)alkoxy group, and a CN group; R1 and R2 are a hydrogen atom or a (C1-C3)alkyl group; with the proviso that when R and R′ are not simultaneously a hydrogen atom: when n is 1, R is not a methyl group in an ortho or para position with respect to N, when R′ is a hydrogen atom, R is not a bromine atom or a chlorine atom, and when R is a hydrogen atom, R is not a methyl or ethyl group, a —COOH group, a —COOC2H5 group, or a bromine atom that is in an ortho position of the bond linked to NR″.
公开/授权文献
- US09908869B2 Compounds useful for treating aids 公开/授权日:2018-03-06
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