发明申请
- 专利标题： ANTIBODIES THAT BIND TO OX40 AND THEIR USES
- 专利标题（中）： 绑定到OX40的抗体及其使用
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申请号： US14222421申请日： 2014-03-21
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公开(公告)号： US20140294824A1公开(公告)日： 2014-10-02
- 发明人: Antoine ATTINGER , Stanislas Blein , Jonathan Albert Back , Rami Lissilaa , Samuel Hou
- 申请人： GLENMARK PHARMACEUTICALS S.A.
- 申请人地址： CH La Chaux-de-Fonds
- 专利权人： GLENMARK PHARMACEUTICALS S.A.
- 当前专利权人： GLENMARK PHARMACEUTICALS S.A.
- 当前专利权人地址： CH La Chaux-de-Fonds
- 主分类号： C07K16/28
- IPC分类号： C07K16/28
摘要：
The present invention relates to antagonist antibodies or fragments thereof that bind to human OX40. More specifically, the present invention relates to an antagonist antibody or fragment thereof that binds to human OX40 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 1, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 2, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 3; and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 4, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 5 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 6.
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