发明申请
- 专利标题： IMMUNE TOLERANCE INDUCER
- 专利标题（中）： 免疫耐受性感应器
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申请号： US14237763申请日： 2012-07-13
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公开(公告)号： US20140294869A1公开(公告)日： 2014-10-02
- 发明人: Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
- 申请人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
- 专利权人： Napajen Pharma, Inc.
- 当前专利权人： Napajen Pharma, Inc.
- 优先权： JPPCT/JP2011/068265 20110810; JPPCT/JP2012/053583 20120215
- 国际申请： PCT/JP2012/067950 WO 20120713
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C12N15/113
摘要：
An object of the present invention is to provide a drug and a method for effectively inducing donor-specific immune tolerance in a recipient in transplantation therapy. A complex of an siRNA for a costimulatory factor and schizophyllan is delivered to a Dectin-1 expressing cell which specifically recognizes schizophyllan to regulate the function of the Dectin-1 expressing cell, and therefore can induce immunosuppression effect as well as induce immune tolerance effectively.
公开/授权文献
- US09801929B2 Immune tolerance inducer 公开/授权日：2017-10-31
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