发明申请
US20140315916A1 MACROCYCLES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
有权
增加p53活性及其用途的MACROCYCLES
- 专利标题： MACROCYCLES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
- 专利标题（中）： 增加p53活性及其用途的MACROCYCLES
-
申请号： US14354303申请日： 2012-10-23
-
公开(公告)号： US20140315916A1公开(公告)日： 2014-10-23
- 发明人: Latha G. Nair , Stephane L. Bogen , Ronald J. Doll , Yao Ma , Yuan Tian
- 申请人： Latha G. Nair , Stephane L. Bogen , Ronald J. Doll , Yao Ma , Yuan Tian
- 国际申请： PCT/US2012/061403 WO 20121023
- 主分类号： C07D498/14
- IPC分类号： C07D498/14
摘要：
The present invention provides a compound of Formula (1): as described herein or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
公开/授权文献
- US08987274B2 Macrocycles that increase p53 activity and the uses thereof 公开/授权日：2015-03-24
信息查询
