发明申请
- 专利标题: VACCINE PREPARATION FOR CANCER TREATMENT
- 专利标题(中): 用于癌症治疗的疫苗制剂
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申请号: US14241321申请日: 2012-08-30
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公开(公告)号: US20140322344A1公开(公告)日: 2014-10-30
- 发明人: Hiroshi Shiku , Naozumi Harada , Daisuke Muraoka , Kazunari Akiyoshi
- 申请人: Hiroshi Shiku , Naozumi Harada , Daisuke Muraoka , Kazunari Akiyoshi
- 申请人地址: JP Tokyo JP Tsu-shi
- 专利权人: National University Corporation Tokyo Medical and Dental University,MIE University
- 当前专利权人: National University Corporation Tokyo Medical and Dental University,MIE University
- 当前专利权人地址: JP Tokyo JP Tsu-shi
- 优先权: JP2011-189234 20110831
- 国际申请: PCT/JP2012/071979 WO 20120830
- 主分类号: A61K39/385
- IPC分类号: A61K39/385 ; A61K39/39
摘要:
A vaccine preparation for treating cancer includes a complex of a hydrophobized polysaccharide and at least one synthetic long peptide derived from a tumor-specific antigenic protein and/or a pathogen-derived antigenic protein. The at least one synthetic long peptide contains at least one CD8+ cytotoxic T-cell recognition epitope and at least one CD4+ helper T-cell recognition epitope. The complex is simultaneously administered to the patient with at least one immunopotentiating agent.
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